A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter
Author
Summary, in English
In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.
Publishing year
2001
Language
English
Pages
197-202
Publication/Series
FEMS Microbiology Letters
Volume
199
Issue
2
Document type
Journal article
Publisher
Oxford University Press
Topic
- Microbiology in the medical area
Keywords
- Cytochrome P450
- AbrB
- FatR
- Bacillus subtilis
Status
Published
Research group
- Microbiology Group
ISBN/ISSN/Other
- ISSN: 1574-6968