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A novel diffusible substance can overcome the apparent AbrB repression of the Bacillus subtilis fatR promoter

Author

Summary, in English

In this work we present evidence for a novel diffusible extracellular factor that modulates gene expression in Bacillus subtilis. The factor was found when studying the regulation of the fatR-cyp102A3 operon. In a Spo0A(-) mutant expression of the fatR-cyp102A3 operon was almost abolished. The fatR-cyp102A3 expression defect of a Spo0A(-) mutant could be overcome either by a mutation in the abrB gene or by a diffusible substance excreted by wild-type, abrB mutant and abrB-spo0A double mutant strains.

Publishing year

2001

Language

English

Pages

197-202

Publication/Series

FEMS Microbiology Letters

Volume

199

Issue

2

Document type

Journal article

Publisher

Oxford University Press

Topic

  • Microbiology in the medical area

Keywords

  • Cytochrome P450
  • AbrB
  • FatR
  • Bacillus subtilis

Status

Published

Research group

  • Microbiology Group

ISBN/ISSN/Other

  • ISSN: 1574-6968