Prediction of Intradialytic Hypotension Using Photoplethysmography
Author
Summary, in English
Intradialytic hypotension is the most common acute complication during conventional hemodialysis treatment. Prediction of such events is highly desirable in clinical routine for prevention. This paper presents a novel prediction method of acute symptomatic hypotension in which the photoplethysmographic signal is analyzed with respect to changes in amplitude, reflecting vasoconstriction, and cardiac output. The method is based on a statistical model in which the noise is assumed to have Laplacian amplitude distribution. The performance is evaluated on 11 hypotension-prone patients who underwent hemodialysis treatment, resulting in seven events with acute symptomatic hypotension and 17 without. The photoplethysmographic signal was continuously acquired during treatment as was information on blood pressure and oxygen saturation. Using leave-one-out cross validation, the proposed method predicted six out of seven hypotensive events, while producing 1 false prediction out of 17 possible. The performance was achieved when the prediction threshold was chosen to be in the range 57%-65% of the photoplethysmographic envelope at treatment onset.
Publishing year
2010
Language
English
Pages
1611-1619
Publication/Series
IEEE Transactions on Biomedical Engineering
Volume
57
Issue
7
Document type
Journal article
Publisher
IEEE - Institute of Electrical and Electronics Engineers Inc.
Topic
- Medical Engineering
Keywords
- signal
- pulse oximetry
- Hemodialysis
- intradialytic hypotension
- vasoconstriction
- processing
Status
Published
Research group
- Signal Processing
ISBN/ISSN/Other
- ISSN: 1558-2531