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Ultrahydrophobic properties of porous silicon for surface based bioanalysis

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Author

Editor

  • Viovy Jean-Louis
  • Patrick Tabeling
  • Stephanie Descroix
  • Laurent Malaquin

Summary, in English

Previously we reported the extreme water repellency of randomly organized macro-/nanoporous silicon surfaces [1]. The texturized silicon with hierarchical porous structure in micrometer and nanometer scale was shown to exhibit the superhydrophobic behaviour. Contact angles as high as 176º can be easily achieved with further fluoroalkylsilane modification of the porous surfaces. Porous silicon technology is compatible with the silicon patterning techniques allowing easy integration of the ultrahydrophobic properties into microfluidic and lab-on-a-chip devices for a new generation of surface based bioanalysis. In this paper we report the fabrication of ultrahydrophobic porous silicon channels and ultrahydrophobic nanovial arrays. Also the MALDI-TOF MS (matrix assisted laser desorption/ionization time-of-flight mass-spectrometry) target anchor chip composed of the hydrophilic anchor points for sample deposition surrounded by the ultrahydrophobic porous area is reported. Such anchor chip allowed the deposition of large sample volumes providing the strategy to improve MALDI-TOF MS sensitivity.

Publishing year

2007

Language

English

Pages

1046-1047

Publication/Series

Micro Total Analysis Systems 2007, Proceedings of µTAS 2007 Conference

Volume

2

Document type

Conference paper

Publisher

Chemical and Biological Microsystems Society

Topic

  • Medical Engineering
  • Analytical Chemistry

Keywords

  • MALDI-TOF MS
  • water repellency
  • porous silicon
  • superhydrophobic
  • microfluidics

Conference name

Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference date

2007-10-07 - 2007-10-11

Conference place

Paris, France

Status

Published

ISBN/ISSN/Other

  • ISBN: 978-0-9798064-0-7