Genomics and the irreducible nature of eukaryote cells
Author
Summary, in English
Large-scale comparative genomics in harness with proteomics has substantiated fundamental features of eukaryote cellular evolution. The evolutionary trajectory of modern eukaryotes is distinct from that of prokaryotes. Data from many sources give no direct evidence that eukaryotes evolved by genome fusion between archaea and bacteria. Comparative genomics shows that, under certain ecological settings, sequence loss and cellular simplification are common modes of evolution. Subcellular architecture of eukaryote cells is in part a physical-chemical consequence of molecular crowding; subcellular compartmentation with specialized proteomes is required for the efficient functioning of proteins.
Department/s
Publishing year
2006
Language
English
Pages
1011-1014
Publication/Series
Science
Volume
312
Issue
5776
Document type
Journal article review
Publisher
American Association for the Advancement of Science (AAAS)
Topic
- Biological Sciences
Status
Published
Research group
- Microbial Ecology
ISBN/ISSN/Other
- ISSN: 1095-9203