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Proteomics principles and challenges

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Author

Summary, in English

Proteomics studies rely on high-resolving separation techniques whereby the biological complexity can be unraveled. Both gel-based and liquid-phase separation principles are needed in order to mine deeper into the low abundant area of the proteins expressed in human cell samples. The expression levels that can be reached today with proteomics technology are still only reaching part of all proteins present in complex biological samples. The challenge to be met is not an easy task and will, in many aspects, be determined by the speed and success whereby the analytical field can make milestone progress. Examples will be given from our research group on proteomics studies, as well as principles and challenges within this research area.

Publishing year

2004

Language

English

Pages

829-837

Publication/Series

Pure and Applied Chemistry

Volume

76

Issue

4

Document type

Journal article

Publisher

IUPAC

Topic

  • Analytical Chemistry

Status

Published

ISBN/ISSN/Other

  • ISSN: 0033-4545