Estimating the distribution of the G2 phase duration from flow cytometric histograms
Author
Summary, in English
A mathematical model, based on branching processes, is proposed to interpret BrdUrd DNA FCM-derived data. Our main interest is in determining the distribution of the G2 phase duration. Two different model classes involving different assumptions on the distribution of the G2 phase duration are considered. Different assumptions of the G2 phase duration result in very similar distributions of the S phase duration and the estimated means and standard deviations of the G2 phase duration are all in the same range.
Publishing year
2008
Language
English
Pages
1-17
Publication/Series
Mathematical Biosciences
Volume
211
Issue
1
Document type
Journal article
Publisher
Elsevier
Topic
- Cancer and Oncology
Keywords
- Cell cycle progression
- Branching process
- G2 phase duration
- Flow cytometry
Status
Published
ISBN/ISSN/Other
- ISSN: 0025-5564