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Protein microchip bioassay with dual fluorescent- and MALDI read-out.

Author

Summary, in English

Protein Microchip Array technology makes it possible to examine patterns of protein expressions and modifications. Current technologies such as two-dimensional get electrophoresis (2-DE) in combination with mass spectrometry allows the identification of biologically relevant proteins with high resolving power, but has also considerable limitations. Most spots observed in 2-DE are from high abundance proteins while low signaling proteins are highly suppressed. Protein microarrays have a potential to speed up the discovery of new markers and targets of interest to the pharmaceutical industry. The technique is also readily compatible with high-throughput applications.

Publishing year

2005

Language

English

Pages

466-468

Publication/Series

Micro Total Analysis Systems 2004, Vol 1

Issue

296

Document type

Conference paper

Publisher

Springer

Topic

  • Medical Engineering

Keywords

  • fluorescence readout
  • MALDI-TOF read-out
  • immunoassay

Conference name

8th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference date

2004-09-26 - 2004-09-30

Conference place

Malmo, Sweden

Status

Published

ISBN/ISSN/Other

  • ISSN: 0260-6291