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Fifteen-Piconewton Force Detection from Neural Growth Cones Using Nanowire Arrays

Author

Summary, in English

We used epitaxially grown monodisperse nanowire arrays to measure cellular forces with a spatial resolution of 1 mu m. Nerve cells were cultured on the array and cellular forces were calculated from the displacement of the nanowire tips. The measurements were done in situ on live cells using confocal microscopy, Forces down to 15 pN were measured on neural growth cones, showing that this method can be used to study the Fine details of growth-cone dynamics.

Publishing year

2010

Language

English

Pages

782-787

Publication/Series

Nano Letters

Volume

10

Issue

3

Document type

Journal article

Publisher

The American Chemical Society (ACS)

Topic

  • Nano Technology

Keywords

  • neuron
  • nanowire
  • picoNewton
  • Mechanosensing
  • cellular force

Status

Published

ISBN/ISSN/Other

  • ISSN: 1530-6992