Review of cell and particle trapping in microfluidic systems.

Summary, in English

The ability to obtain ideal conditions for well-defined chemical microenvironments and controlled temporal chemical and/or thermal variations holds promise of high-resolution cell response studies, cell-cell interactions or e.g. proliferation conditions for stem cells. It is a major motivation for the rapid increase of lab-on-a-chip based cell biology research. In view of this, new chip-integrated technologies are at an increasing rate being presented to the research community as potential tools to offer spatial control and manipulation of cells in microfluidic systems. This is becoming a key area of interest in the emerging lab-on-a-chip based cell biology research field. This review focuses on the different technical approaches presented to enable trapping of particles and cells in microfluidic system.

• Author: Johan Nilsson; Mikael Evander; Björn Hammarström; Thomas Laurell
• Department/s: Department of Biomedical Engineering
• Publishing year: 2009
• Language: English
• Pages: 141-157
• Publication/Series: Analytica Chimica Acta
• Volume: 649
• Issue: 2
• Links: http://dx.doi.org/10.1016/j.aca.2009.07.017
• Document type: Journal article
• Publisher: Elsevier
• Topic: Analytical Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 1873-4324