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Ethanol reduces rCBF activation of left dorsolateral prefrontal cortex during a verbal fluency task

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Author

Summary, in English

Measurements of regional cerebral blood flow were made in 20 healthy young male subjects during sobriety and inebriation (0.06 % blood alcohol) during rest and during performance of a word fluency test. Word production was decreased during inebriation. The activation within the frontotemporal part of the left dorsolateral prefrontal cortex was preserved during intoxication. During inebriation no activation response to the word fluency test was seen in the anterior prefrontal part of the dorsolateral prefrontal cortex. This area showed a marked activation response during sobriety. Hemispheric function and specialization seems thus to be adversely affected by ethanol.

Publishing year

2001

Language

English

Pages

197-215

Publication/Series

Brain and Language

Volume

77

Issue

2

Document type

Journal article

Publisher

Elsevier

Topic

  • Psychology

Keywords

  • DLPFC
  • verbal fluency
  • cortical asymmetry
  • ethanol
  • functional lateralization
  • Key Words: regional cerebral blood flow

Status

Published

ISBN/ISSN/Other

  • ISSN: 1090-2155