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Robustness of metabolic maps

Author

Summary, in English

With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.

Department/s

Publishing year

2004

Language

English

Pages

589-593

Publication/Series

Journal of Bioinformatics and Computational Biology

Volume

2

Issue

3

Document type

Journal article

Publisher

World Scientific Publishing

Topic

  • Biological Sciences

Keywords

  • Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways

Status

Published

Research group

  • Microbial Ecology

ISBN/ISSN/Other

  • ISSN: 0219-7200