Crossed over repair of the femoral sensory and motor branches influences N-CAM
Author
Summary, in English
N-CAM, expressed by non-myelinating Schwann cells, was investigated by immunohistochemistry in transected rat femoral nerves, which were repaired either using a straight or a crossed over technique. N-CAM staining covered 30 and 11% of the cross-sectional area of and motor branches, respectively, in uninjured nerves. After 3 days there was a transient smaller area of N-CAM staining following both the repairs. After a straight repair N-CAM area increased to the control values in both branches. In contrast, a crossed over repair resulted in a continuous increase of N-CAM in the motor branch, whereas the area in the sensory branch returned slowly to control values. N-CAM is influenced by an intentionally misdirected outgrowth of motor and sensory axons after nerve repair. NeuroReport 21:841-845 (C) 2010 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Publishing year
2010
Language
English
Pages
841-845
Publication/Series
NeuroReport
Volume
21
Issue
12
Document type
Journal article
Publisher
Lippincott Williams & Wilkins
Topic
- Neurosciences
Keywords
- neurofilaments
- nerve repair
- nerve regeneration
- N-CAM
- axons
- misdirection
- non-myelinating
- Schwann cells
Status
Published
Research group
- Hand Surgery, Malmö
ISBN/ISSN/Other
- ISSN: 1473-558X