Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process
Author
Summary, in English
This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel "systematic evolution of ligands by exponential enrichment" (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during the SELEX process. The proposed device with an optimally designed hydraulic resistance-balanced channel network could be feasible and utilized as a multiplex selection module for a parallel SELEX process. (c) 2011 The Japan Society of Applied Physics
Department/s
Publishing year
2011
Language
English
Pages
05-06
Publication/Series
Japanese Journal of Applied Physics
Volume
50
Issue
6
Document type
Journal article
Publisher
IOP Publishing
Topic
- Medical Engineering
Status
Published
ISBN/ISSN/Other
- ISSN: 0021-4922