Acoustic trapping of cells in a microfluidic format

Summary, in English

This paper presents, for the first time, non-contact acoustic trapping of cells in a

microfluidic format. The employed acoustic force maintains the cells in the center of a

fluidic channel while allowing for perfusion of e.g. nutrients or drugs as well as optical

monitoring of the cells. Neural stem cells have been acoustically trapped and tested for

viability after 15 minutes of ultrasonic radiation. It is also shown that it is possible to grow

yeast cells suspended in an acoustic standing wave while perfusing with cell media.

• Author: Mikael Evander; Linda Johansson; Tobias Lilliehorn; Magnus Lindvall; Jure Piskur; Monica Almqvist; Stefan Johansson; Thomas Laurell; Johan Nilsson
• Editor: Klavs F. Jensen; Jongyoon Han; D. Jed Harrison; Joel Voldman
• Department/s: Department of Biomedical Engineering; Child and Adolescent Psychiatry; Molecular Cell Biology
• Publishing year: 2005
• Language: English
• Pages: 515-517
• Publication/Series: Proceedings of µTAS 2005 Conference
• Volume: 1
• Document type: Conference paper
• Publisher: Transducer Research Foundation
• Topic: Biological Sciences; Medical Engineering
• Keywords: Trapping; Microfluidic; Cells; Acoustic
• Conference name: Micro Total Analysis Systems 2005
• Conference date: 2005-10-09 - 2005-10-13
• Conference place: Boston, United States
• Status: Published
• ISBN/ISSN/Other: ISBN: 0-9743611-1-9