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Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on Väli et al. (2008).

Author

Summary, in English

Abstract A recent study by Väli et al. (2008) highlights that microsatellites will often provide a poor prediction of the genome-wide nucleotide diversity of wild populations, but does not fully explain why. To clarify and stress the importance of identity disequilibrium and marker variability for correlations between multilocus heterozygosity and genome-wide genetic variability, we performed a simple simulation with different types of markers, corresponding to microsatellites and SNPs, in populations with different inbreeding history. The importance of identity disequilibrium was apparent for both markers and there was a clear impact of marker variability.

Publishing year

2010

Language

English

Pages

851-855

Publication/Series

Molecular Ecology

Volume

19

Document type

Journal article

Publisher

Wiley-Blackwell

Topic

  • Biological Sciences

Keywords

  • identity disequilibrium
  • genetic diversity
  • heterozygosity
  • inbreeding
  • microsatellites

Status

Published

Research group

  • Molecular Ecology and Evolution Lab

ISBN/ISSN/Other

  • ISSN: 0962-1083