Do microsatellites reflect genome-wide genetic diversity in natural populations? A comment on Väli et al. (2008).
Author
Summary, in English
Abstract A recent study by Väli et al. (2008) highlights that microsatellites will often provide a poor prediction of the genome-wide nucleotide diversity of wild populations, but does not fully explain why. To clarify and stress the importance of identity disequilibrium and marker variability for correlations between multilocus heterozygosity and genome-wide genetic variability, we performed a simple simulation with different types of markers, corresponding to microsatellites and SNPs, in populations with different inbreeding history. The importance of identity disequilibrium was apparent for both markers and there was a clear impact of marker variability.
Department/s
Publishing year
2010
Language
English
Pages
851-855
Publication/Series
Molecular Ecology
Volume
19
Links
Document type
Journal article
Publisher
Wiley-Blackwell
Topic
- Biological Sciences
Keywords
- identity disequilibrium
- genetic diversity
- heterozygosity
- inbreeding
- microsatellites
Status
Published
Research group
- Molecular Ecology and Evolution Lab
ISBN/ISSN/Other
- ISSN: 0962-1083