The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

Effect of alpha-ketoglutarate given to pregnant sows on the development of the humerus and femur in newborns

På svenska

Author

  • E Sliwa
  • S Kowalik
  • MR Tatara
  • W Krupski
  • P Majcher
  • I Luszczewska-Sierakowska
  • Stefan Pierzynowski
  • T Studzinski

Summary, in English

Alpha-ketoglutarate (AKG) was given to pregnant sows every day starting from the 91(st) d of pregnancy to farrowing. At the same time control pregnant sows were treated in the same way with physiological saline (PhS). Newborn piglets from the experimental (AKG) and control (PhS) mothers were euthanised in 1 h after their birth, and the femora and humeri were isolated and frozen at -25 degrees C until further analyses. Using quantitative computed tomography (QCT) method, volumetric bone density of the cortical and trabecular bone compartments were estimated. Moreover, geometrical and mechanical parameters of the bones and the level of osteocalcin and alkaline phosphatase activity in serum were determined. It was found that the administration of AKG to pregnant sows during 24 d before parturition decreased bone density in their newborns.

Department/s

Publishing year

2005

Language

English

Pages

117-120

Publication/Series

Bulletin of the Veterinary Institute in Puławy

Volume

49

Issue

1

Document type

Journal article

Publisher

National Veterinary Research Institute

Topic

  • Zoology

Keywords

  • alpha-ketoglutarate
  • piglets
  • sow
  • pregnancy
  • bone formation

Status

Published

ISBN/ISSN/Other

  • ISSN: 0042-4870