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KEMM15. The course aims to provide an in-depth understanding of proteins with an emphasis on structure and its connection to biological functions. The course treats the principles that determine these properties and the methods, mainly X-ray crystallography, that is used to study them within modern molecular protein science.
Lectures: Polypeptide conformations. The secondary and three-dimensional structure of proteins, structural classification and structure databases. Prediction and modelling of protein structure. The stability of proteins, dynamics, the interaction in proteins: packing and electrostatics. Ligand binding and structure-based design of drugs. Principles for X-ray crystallography and other methods such as small angle X-ray scattering, neutron scattering etc.
Laboratory work and computer exercises: Provide training in the relevant theoretical and experimental methods that are described for studying protein structure and dynamics.
More information can be found at http://www.kemi.lu.se/utbildning/avancerad/KEMM15/