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Early posttraumatic pulmonary platelet trapping and its potentiation by oral pretreatment with alcohol

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Author

Summary, in English

Soft tissue trauma is associated with platelet aggregation and sequestration in the lungs. This is believed to be an early step in the later development of adult respiratory distress syndrome. In the present experiment using a new method for in vivo dynamic studies of platelet sequestration, we wanted to evaluate the effect of soft tissue trauma on pulmonary platelet trapping in pigs and the influence of acute alcohol intoxication. The results show that significant pulmonary platelet trapping is registered within minutes of trauma and that alcohol significantly increases platelet sequestration in the lungs. This indicates an increased risk for posttraumatic pulmonary problems in alcohol-intoxicated trauma victims

Publishing year

1986

Language

English

Pages

216-220

Publication/Series

The American Journal of Surgery

Volume

151

Issue

2

Document type

Journal article

Publisher

Elsevier

Topic

  • Surgery

Status

Published

ISBN/ISSN/Other

  • ISSN: 1879-1883