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Antisense RNAs everywhere?

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Author

Summary, in English

In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.

Publishing year

2002

Language

English

Pages

223-226

Publication/Series

Trends in Genetics

Volume

18

Issue

5

Document type

Journal article review

Publisher

Elsevier

Topic

  • Biological Sciences

Keywords

  • bacteria
  • plasmid
  • riboregulator
  • antisense RNA
  • non-coding RNA
  • gene silencing

Status

Published

ISBN/ISSN/Other

  • ISSN: 1362-4555