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A Gaussian mixture model for time-frequency analysis during atrial fibrillation electrocardiograms

Author

Summary, in English

During atrial fibrillation (AF), time-frequency analysis of atrial signal has been applied to describe fibrillatory frequency trends. Recently, temporal changes in spectral shape have been investigated using the spectral profile technique. This profile is computed recursively by fitting each short-time log-spectrum to a spectral template, using amplitude scaling and frequency shifting. The purpose of the present study was to develop a Gaussian mixture model of the spectral profile in order to characterize the shape of AF waveforms. A novel index is introduced, the so-called harmonic index (HI), which reflects properties of the fundamental frequency peak and related harmonics peaks as estimated from the model. The index was tested on recordings from 9 patients with persistent AF, obtained before and after exercise testing. The HI succeeded in monitoring the response to exercise, i.e. change in the spectral profile to a less harmonic pattern, which is consistent with a reduction in AF organization (HI: 0.61±0.11 vs. 0.50±0.19, rest vs. exercise; p≪0.05).

Publishing year

2007

Language

English

Pages

271-274

Publication/Series

29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2007.

Document type

Conference paper

Publisher

IEEE - Institute of Electrical and Electronics Engineers Inc.

Topic

  • Electrical Engineering, Electronic Engineering, Information Engineering

Conference name

29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2007.

Conference date

2007-08-22 - 2007-08-26

Status

Published

Research group

  • Signal Processing Group

ISBN/ISSN/Other

  • ISSN: 1557-170X
  • ISBN: 978-1-4244-0788-0