The aim of our research is to identify genetic and immunological risk factors and predictive factors for type 1 diabetes, and ultimately to prevent the disease through primary or secondary prevention.
The research is based upon our large prospective population-based studies. Diabetes Prediction in Skåne (DiPiS) and The Environmental Determinants of Diabetes in the young (TEDDY), screening for autoantibodies in relatives within TrialNet and a number of clinical trials aiming to prevent or delay the disease (Figure 1).
In our prospective cohorts of children with risk for type 1 diabetes, we have shown that the children followed are diagnosed early with less symptom and serious disease. To prevent or delay type 1 diabetes in children with autoimmunity would be of uttermost importance.