Rare emergence of symptoms during long-term asymptomatic E. coli 83972 carriage, without altered virulence factor repertoire.

Summary, in English

Asymptomatic bacteriuria (ABU), established by intravesical inoculation of E.coli 83972, is protective in patients with recurrent UTI. In an RCT cross-over study, two patients developed three symptomatic UTI episodes while carrying E.coli 83972. This study examined if a reacquisition of virulence by symptom isolates may account for the switch from ABU to symptomatic UTI.

• Author: Béla Köves; Ellaine Salvador; Jenny Grönberg Hernandez; Jaroslaw Zdziarski; Björn Wullt; Catharina Svanborg; Ulrich Dobrindt
• Department/s: Division of Microbiology, Immunology and Glycobiology - MIG
• Publishing year: 2014
• Language: English
• Pages: 519-528
• Publication/Series: Journal of Urology
• Volume: 191
• Issue: 2
• Links: http://www.ncbi.nlm.nih.gov/pubmed/23911604?dopt=Abstract; http://dx.doi.org/10.1016/j.juro.2013.07.060
• Document type: Journal article
• Publisher: Lippincott Williams & Wilkins
• Topic: Urology and Nephrology
• Status: Published
• ISBN/ISSN/Other: ISSN: 1527-3792