DIANA - algorithmic improvements for analysis of data-independent acquisition MS data.

Summary, in English

Data independent acquisition mass spectrometry has emerged as a reproducible and sensitive alternative in quantitative proteomics, where parsing the highly complex tandem mass spectra requires dedicated algorithms. Recently, targeted data extraction was proposed as a novel analysis strategy for this type of data, but it is important to further develop these concepts to provide quality-controlled, interference-adjusted and sensitive peptide quantification.

• Author: Johan Teleman; Hannes Röst; George Rosenberger; Uwe Schmitt; Lars Malmström; Johan Malmström; Fredrik Levander
• Department/s: Department of Immunotechnology; Infection Medicine (BMC); Infection Medicine Proteomics
• Publishing year: 2015
• Language: English
• Pages: 555-562
• Publication/Series: Bioinformatics
• Volume: 31
• Issue: 4
• Full text: - 3 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25348213?dopt=Abstract; http://dx.doi.org/10.1093/bioinformatics/btu686
• Document type: Journal article
• Publisher: Oxford University Press
• Topic: Infectious Medicine
• Status: Published
• Research group: Infection Medicine Proteomics
• ISBN/ISSN/Other: ISSN: 1367-4803