MLL/GAS7 fusion in a pediatric case of t(11;17)(q23;p13)-positive precursor B-cell acute lymphoblastic leukemia
Author
Summary, in English
AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular genetic features of MLL/GAS7 and the clinical impact of t(11;17) are discussed.
Department/s
Publishing year
2006
Language
English
Pages
1287-1288
Publication/Series
Haematologica
Volume
91
Issue
9
Links
Document type
Journal article (letter)
Publisher
Ferrata Storti Foundation
Topic
- Hematology
Keywords
- GAS7
- MLL
- ALL
- translocation
- fusion
Status
Published
ISBN/ISSN/Other
- ISSN: 1592-8721