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Tobacco smoke as a major source of endotoxin in indoor air

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Author

  • L Larsson
  • Bogumila Szponar
  • Christina Pehrson
  • Aleksandra Sebastian
  • J Rybka

Summary, in English

Mass spectrometry was used to determine the endotoxin (lipopolysaccharide, LPS) marker 3-hydroxytetradecanoic acid and 3-deoxy -D-manno-2-octulosonic acid in cigarette tobacco and smoke particles. Tobacco from cigarettes of different brands purchased in four different countries in Europe and Asia contained similar amounts of LPS. Indoor exposure to environmental tobacco smoke (ETS) in rooms of smoking students entailed inhalation of LPS in amounts that were 6-60 times higher than in student rooms without ongoing smoking. The fact that cigarette smoke contains large amounts of endotoxin may partly explain the high prevalence of respiratory disorders among smokers and may also draw attention to a hitherto unknown or neglected risk factor of ETS.

Publishing year

2005

Language

English

Pages

1655-1658

Publication/Series

Indoor Air 2005: Proceedings of the 10th International Conference on Indoor Air Quality and Climate, Vols 1-5

Document type

Conference paper

Publisher

Tsinghua University Press

Topic

  • Microbiology in the medical area

Keywords

  • Kdo
  • respiratory disorders among smokers
  • acids
  • 3-hydroxy fatty
  • chemical markers
  • indoor air
  • endotoxin
  • tobacco smoke

Conference name

10th International Conference on Indoor Air Quality and Climate (Indoor Air 2005)

Conference date

2005-09-04 - 2005-09-09

Conference place

Beijing, China

Status

Published