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REPRESENTATIVE SELECTION OF PROTEINS BASED ON NUCLEAR FAMILIES

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Author

Summary, in English

The selection of unbiased representatives from a large database is complicated by the requirement for the chosen entries to be not only genuinely different from each other but also typical for the family of related entries. A method satisfying this 2-fold objective was developed by equipping complete linkage clustering with a novel noise elimination procedure to deal with overlapping cluster structure, A total of 200 nuclear families of truly related Brookhaven Protein Data Bank structures were generated, from which any entry can be chosen to represent its family.

Publishing year

1995

Language

English

Pages

501-503

Publication/Series

Protein Engineering

Volume

8

Issue

5

Document type

Journal article (letter)

Publisher

Oxford University Press

Topic

  • Medical Genetics

Keywords

  • COMPLETE LINKAGE CLUSTERING
  • NOISE ELIMINATION
  • PDB FAMILIES
  • REPRESENTATIVE SELECTION

Status

Published

ISBN/ISSN/Other

  • ISSN: 1460-213X