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High NT-proBNP Is a Strong Predictor of Outcome in Elderly Heart Failure Patients.

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Author

Summary, in English

All patients older than 65 years (184 men; mean age, 78+/-0.8 years/181 women; mean age, 82+/-0.6 years) seeking medical attention at the Lund University Hospital Emergency Clinic during a 2-year period who had an N-terminal prohormone brain natriuretic peptide (NT-proBNP) value >2000 pg/mL were followed up for survival. Mortality in the entire population was 21% after 3 months, 35% after 1 year, and 40% after 2 years. Multivariate analysis indicated that the NT-proBNP level and the New York Heart Association (NYHA) functional class were stronger predictors of mortality than were echocardiographic estimation of left ventricular ejection fraction or chest radiography. Patients who survived the first year were younger, had higher systolic blood pressure, had lower plasma creatinine, had lower inflammatory activity, and were treated with lower doses of furosemide. The results indicate that in this population, NT-proBNP level together with assessment of NYHA class gives the best prognostic information of 1-year mortality. (Am J Geriatr Cardiol. 2008;17:13-20).

Publishing year

2008

Language

English

Pages

13-20

Publication/Series

American Journal of Geriatric Cardiology

Volume

17

Issue

1

Document type

Journal article

Publisher

John Wiley & Sons Inc.

Topic

  • Other Clinical Medicine
  • Environmental Health and Occupational Health

Status

Published

ISBN/ISSN/Other

  • ISSN: 1751-715X