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Biologically active metabolites from the basidiomycete Limacella illinita (Fr.) Murr.

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Author

Summary, in English

In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane sesquiterpene 4a was found to be inactive in the assays performed here. Limacellone (3), which appeared to be related with the illinitones 1 and 2, has a new C-15 carbon skeleton. It is possible that compounds 1, 2 and 3 are terpenoids/secoterpenoids, but their biosyntheses were not investigated.

Publishing year

2007

Language

English

Pages

808-812

Publication/Series

Zeitschrift fuer Naturforschung. Section C: A Journal of Biosciences

Volume

62

Issue

11-12

Document type

Journal article

Publisher

Verlag der Zeitschrift für Naturforschung

Topic

  • Organic Chemistry

Keywords

  • limacellone
  • Limacella illinita
  • illinitones
  • 11-desoxyeleganthol

Status

Published

ISBN/ISSN/Other

  • ISSN: 0939-5075