Comparison of automated von Willebrand factor activity assays.

Summary, in English

Von Willebrand Disease (VWD) is the most common inherited bleeding disorder. Measurement of von Willebrand factor (VWF) activity in plasma is often based on platelet agglutination stimulated by the ristocetin cofactor activity. Novel assays, based on latex beads with recombinant glycoprotein Ib instead of platelets, have recently been developed but it is unclear whether these can improve the diagnostic capability for VWD.

• Author: Annette Timm; Andreas Hillarp; Malou Philips; Jens P Goetze
• Department/s: Clinical Chemistry, Malmö
• Publishing year: 2015-01-30
• Language: English
• Publication/Series: Thrombosis Research
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25661290?dopt=Abstract; http://dx.doi.org/10.1016/j.thromres.2015.01.027
• Document type: Journal article
• Publisher: Elsevier
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Clinical Chemistry, Malmö
• ISBN/ISSN/Other: ISSN: 1879-2472