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Lactobacillus acidophilus autolysins inhibit Helicobacter pylori in vitro

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Author

  • Graciela L. Lorca
  • Torkel Wadström
  • Graciela Font de Valdez
  • Åsa Ljungh

Summary, in English

Antibacterial activity of 17 strains of lactobacilli was tested against 10 strains of H. pylori. The inhibition observed was related to the acid production and the low pH attained. No relationship between CagA phenotype of H, pylori strains and tolerance to lactic acid was observed. In mixed cultures, L. acidophilus CRL 639 showed an autolytic behavior after 24 h of culture. At this moment, H. py[ori CCUG17874 showed a decrease of 2 log-cycle, and no viable count was detected after 48 h, The bactericidal effect of L. acidophilus CRL 639 in mixed cultures is related to a proteinaceous compound released after cell lysis.

Publishing year

2001

Language

English

Pages

39-44

Publication/Series

Current Microbiology

Volume

42

Issue

1

Document type

Journal article

Publisher

Springer

Topic

  • Microbiology in the medical area

Status

Published

ISBN/ISSN/Other

  • ISSN: 0343-8651