The browser you are using is not supported by this website. All versions of Internet Explorer are no longer supported, either by us or Microsoft (read more here: https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Please use a modern browser to fully experience our website, such as the newest versions of Edge, Chrome, Firefox or Safari etc.

A novel atlas of gene expression in human skeletal muscle reveals molecular changes associated with aging.

På svenska

Author

Summary, in English

Although high-throughput studies of gene expression have generated large amounts of data, most of which is freely available in public archives, the use of this valuable resource is limited by computational complications and non-homogenous annotation. To address these issues, we have performed a complete re-annotation of public microarray data from human skeletal muscle biopsies and constructed a muscle expression compendium consisting of nearly 3000 samples. The created muscle compendium is a publicly available resource including all curated annotation. Using this data set, we aimed to elucidate the molecular mechanism of muscle aging and to describe how physical exercise may alleviate negative physiological effects.

Publishing year

2015

Language

English

Publication/Series

Skeletal Muscle

Volume

5

Document type

Journal article

Publisher

BioMed Central (BMC)

Topic

  • Medical Genetics

Status

Published

Research group

  • Translational Muscle Research

ISBN/ISSN/Other

  • ISSN: 2044-5040