Changes in glucose-elicited blood metabolite responses following weight loss and long term weight maintenance in obese individuals with impaired glucose tolerance.

Summary, in English

Weight loss improves insulin sensitivity and glucose tolerance in obese subjects with impaired glucose tolerance (IGT), but the long term dynamic effects on blood metabolites other than glucose during an oral glucose tolerance test (OGTT), are largely unknown. Here, we studied changes in OGTT-elicited metabolite patterns in obese subjects during a diet-induced weight loss study.

• Author: Nina Geidenstam; Anders Danielsson; Peter Spégel; Martin Ridderstråle
• Department/s: Diabetes - Clinical Obesity; Diabetes - Molecular Metabolism; EXODIAB: Excellence of Diabetes Research in Sweden
• Publishing year: 2016-01-15
• Language: English
• Pages: 187-197
• Publication/Series: Diabetes Research and Clinical Practice
• Volume: 113
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26809903?dopt=Abstract; http://dx.doi.org/10.1016/j.diabres.2015.12.024
• Document type: Journal article
• Publisher: Elsevier
• Topic: Endocrinology and Diabetes
• Status: Published
• Research group: Diabetes - Clinical Obesity; Diabetes - Molecular Metabolism
• ISBN/ISSN/Other: ISSN: 1872-8227