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Respiratory Inflammation Among Workers Exposed to Airborne Dust With Endotoxins in a Coffee Curing Factory.

Author

  • Bente E Moen
  • Gloria Sakwari
  • Simon H D Mamuya
  • Akwilina V Kayumba
  • Lennart Larsson
  • Christina Pehrson
  • Yohana J Mashalla
  • Magne Bråtveit

Summary, in English

OBJECTIVE:

To study dust exposure and inflammatory reactions in the respiratory tract among coffee curing workers in Tanzania.



METHODS:

A cross-sectional study was conducted in a Tanzanian coffee curing factory. Coffee workers (n = 15) were compared with unexposed controls (n = 18); all workers were nonsmokers. Exhaled nitric oxide was examined using an electrochemistry-based NIOX MINO device. Personal air samples were analyzed for total dust and endotoxins, using gravimetric analysis and the chromogenic Limulus amebocyte lysate endpoint assay, respectively.



RESULTS:

Total dust levels ranged from 0.2 to 27.9 mg/m, and endotoxin levels ranged from 42 to 75,083 endotoxin units/m. Concentrations of exhaled nitric oxide, analyzed by linear regression and adjusted for age (β = 0.57; 95% confidence interval, 0.08 to 1.06; P = 0.02), was higher among coffee workers than among the control group.



CONCLUSION:

The results indicate a relationship between the coffee dust and signs of respiratory inflammation.

Publishing year

2012

Language

English

Pages

847-850

Publication/Series

Journal of Occupational and Environmental Medicine

Volume

54

Issue

7

Document type

Journal article

Publisher

Lippincott Williams & Wilkins

Topic

  • Environmental Health and Occupational Health

Status

Published

ISBN/ISSN/Other

  • ISSN: 1536-5948