Expression analysis of a family of developmentally-regulated cytosolic sulfotransferases (SULTs) in Drosophila.

Summary, in English

We have compared the amino acid sequence of all four cytosolic sulfotransferases (SULTs) in Drosophila and analyzed their spatial expression patterns during development. Three out of four SULTs show distinct expression activity during embryogenesis, while the 4th SULT shows expression only post-embryonically. st1, st3 and st4 are expressed in non-overlapping expression domains mainly confined to organs of the alimentary canal such as esophagus, malphigian tubules, hindgut, as well as in the tracheal system. All these organs are surrounded by the hemolymph suggesting that Drosophila SULTs exert their function in detoxification of substances upon influx from the hemolymph.

• Author: Khalid Fahmy; Stefan Baumgartner
• Department/s: Invertebrate Developmental Biology, Stefan Baumgartner's group
• Publishing year: 2013
• Language: English
• Pages: 44-48
• Publication/Series: Hereditas
• Volume: 150
• Issue: 2-3
• Full text: - 11 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/23865965?dopt=Abstract; http://dx.doi.org/10.1111/j.1601-5223.2013.00006.x
• Document type: Journal article
• Publisher: Wiley-Blackwell
• Topic: Genetics
• Status: Published
• Research group: Invertebrate Developmental Biology, Stefan Baumgartner's group
• ISBN/ISSN/Other: ISSN: 1601-5223