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Cystatin C as a marker of GFR - history, indications, and future research

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Author

  • G Filler
  • A Bokenkamp
  • W Hofmann
  • T Le Bricon
  • C Martinez-Bru
  • Anders Grubb

Summary, in English

Objective: To summarize recent knowledge on the small molecular weight protein cystatin C (cys-C) and its use as a marker of the glomerular filtration rate (GFR). Methods: A multinational expert meeting was held in April 2002 in Marburg, Germany. Contributors summarized their main findings. Conclusions: Cys-C is at least equal if not superior to serum creatinine as a marker of GFR. The independence from height, gender, age. and muscle mass is advantageous. Select patient groups such as children, the elderly, and patients with reduced muscle mass benefit in particular.

Publishing year

2005

Language

English

Pages

1-8

Publication/Series

Clinical Biochemistry

Volume

38

Issue

1

Document type

Journal article review

Publisher

Elsevier

Topic

  • Biochemistry and Molecular Biology

Keywords

  • creatinine
  • cystatin C
  • GFR

Status

Published

ISBN/ISSN/Other

  • ISSN: 1873-2933