Genomic position mapping discrepancies of commercial SNP chips.

Summary, in English

The field of genetics has come to rely heavily on commercial genotyping arrays and accompanying annotations for insights into genotype-phenotype associations. However, in order to avoid errors and false leads, it is imperative that the annotation of SNP chromosomal positions is accurate and unambiguous. We report on genomic positional discrepancies of various SNP chips for human, cattle and mouse species, and discuss their causes and consequences.

• Author: Joao Fadista; Christian Bendixen
• Department/s: Translational Muscle Research; EXODIAB: Excellence of Diabetes Research in Sweden
• Publishing year: 2012
• Language: English
• Publication/Series: PLoS ONE
• Volume: 7
• Issue: 2
• Full text: - 217 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/22363540?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0031025
• Document type: Journal article
• Publisher: Public Library of Science (PLoS)
• Topic: Endocrinology and Diabetes
• Status: Published
• Research group: Genomics, Diabetes and Endocrinology
• ISBN/ISSN/Other: ISSN: 1932-6203