Simultaneous detection of molecular oxygen and water vapor in the tissue optical window using tunable diode laser spectroscopy
Author
Summary, in English
We report on a newly developed diode-laser spectroscopic system for gas detection in scattering
media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to
simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue
optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish
between the two wavelengths. No crosstalk can be observed between the gas contents of the two gas
channels. The system is made compact by using a computer board and performing software based
lock-in detection. The noise floor obtained corresponds to an absorption fraction of about 6 · 10−5
for both oxygen and water vapour. The power of the technique is illustrated by preliminary results
from a clinical trial investigating the human sinuses.
media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to
simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue
optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish
between the two wavelengths. No crosstalk can be observed between the gas contents of the two gas
channels. The system is made compact by using a computer board and performing software based
lock-in detection. The noise floor obtained corresponds to an absorption fraction of about 6 · 10−5
for both oxygen and water vapour. The power of the technique is illustrated by preliminary results
from a clinical trial investigating the human sinuses.
Department/s
Publishing year
2008
Language
English
Pages
2028-2034
Publication/Series
Applied Optics
Volume
47
Issue
12
Full text
Document type
Journal article
Publisher
Optical Society of America
Topic
- Cancer and Oncology
Status
Published
Research group
- Biophotonics
ISBN/ISSN/Other
- ISSN: 2155-3165