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The mouse trap

Author

Summary, in English

Mouse models of asthma are now being used extensively in drug research. However, the successful unravelling of combinatorial interplays of cells and molecules in the murine airways may not be matched by equally successful demonstrations of an asthma-like pathophysiology. Here, Carl Persson, Jonas Erjefalt, Magnus Korsgren and Frank Sundler discuss the fact that major features of asthma may still need to be demonstrated in the airways of allergic mice.

Publishing year

1997

Language

English

Pages

465-467

Publication/Series

Trends in Pharmacological Sciences

Volume

18

Issue

12

Document type

Journal article

Publisher

Elsevier

Topic

  • Cell and Molecular Biology
  • Immunology in the medical area
  • Medicinal Chemistry
  • Pharmacology and Toxicology

Keywords

  • mucosal pathophysiology
  • epithelial changes
  • leukocytes
  • airways disease
  • eosinophils
  • allergy
  • asthma
  • mouse model

Status

Published

Research group

  • Airway Inflammation and Immunology

ISBN/ISSN/Other

  • ISSN: 0165-6147