C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation.

• Author: Leendert Trouw; Sara Nilsson; Isabel Goncalves; Göran Landberg; Anna Blom
• Department/s: Clinical Chemistry, Malmö; Cardiovascular Research - Translational Studies; Cardiovascular Research - Immunity and Atherosclerosis; Pathology, Malmö; Protein Chemistry, Malmö
• Publishing year: 2005
• Language: English
• Pages: 1937-1948
• Publication/Series: Journal of Experimental Medicine
• Volume: 201
• Issue: 12
• Full text: - 3 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=15967823&dopt=Abstract; http://dx.doi.org/10.1084/jem.20050189
• Document type: Journal article
• Publisher: Rockefeller University Press
• Topic: Medicinal Chemistry; Clinical Medicine; Cell and Molecular Biology; Cancer and Oncology
• Status: Published
• Research group: Clinical Chemistry, Malmö; Cardiovascular Research - Translational Studies; Cardiovascular Research - Immunity and Atherosclerosis; Pathology, Malmö; Protein Chemistry, Malmö
• ISBN/ISSN/Other: ISSN: 1540-9538