Comparison of several von Willebrand factor (VWF) activity assays for monitoring patients undergoing treatment with VWF/FVIII concentrates: improved performance with a new modified automated method.

Summary, in English

The ability of von Willebrand factor (VWF) to bind platelet GP Ib and promote platelet plug formation is measured in vitro using the ristocetin cofactor (VWF:RCo) assay. Automated assay systems make testing more accessible for diagnosis, but do not necessarily improve sensitivity and accuracy.

• Author: Andreas Hillarp; K D Friedman; D Adcock-Funk; S Tiefenbacher; W L Nichols; D Chen; M Stadler; B A Schwartz
• Department/s: Clinical Chemistry, Malmö
• Publishing year: 2015
• Language: English
• Pages: 837-845
• Publication/Series: Haemophilia
• Volume: 21
• Issue: 6
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26172561?dopt=Abstract; http://dx.doi.org/10.1111/hae.12703
• Document type: Journal article
• Publisher: Wiley-Blackwell
• Topic: Hematology
• Status: Published
• Research group: Clinical Chemistry, Malmö
• ISBN/ISSN/Other: ISSN: 1351-8216