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Bacterial vaginosis - a microbiological and immunological enigma

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Author

  • U Forsum
  • Elisabet Holst
  • P G Larsson
  • Alejandra Vasquez
  • T Jakobsson
  • I Mattsby-Baltzer

Summary, in English

The development of bacterial vaginosis (BV) among women of childbearing age and the resulting quantitative and qualitative shift from normally occurring lactobacilli in the vagina to a mixture of mainly anaerobic bacteria is a microbiological and immunological enigma that so far has precluded the formulation of a unifying generally accepted theory on the aetiology and clinical course of BV This critical review highlights some of the more important aspects of BV research that could help in formulating new basic ideas respecting the biology of BV not least the importance of the interleukin mediators of local inflammatory responses and the bacterial shift from the normally occurring lactobacilli species: L. crispatus, L. gasseri, L. jensenii, and L. iners to a mixed flora dominated by anaerobic bacteria.

Publishing year

2005

Language

English

Pages

81-90

Publication/Series

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Volume

113

Issue

2

Document type

Journal article review

Publisher

John Wiley & Sons Inc.

Topic

  • Microbiology in the medical area

Keywords

  • immune response
  • taxonomy
  • lactobacilli
  • bacterial vaginosis
  • ecology
  • nugent scoring

Status

Published

ISBN/ISSN/Other

  • ISSN: 1600-0463