Evidence for altered inflammatory and repair responses in symptomatic carotid plaques from elderly patients.

Summary, in English

Most acute cardiovascular events are caused by rupture of an atherosclerotic plaque. The incidence of cardiovascular events increases with age and inflammation is generally considered to be the main cause of increased plaque vulnerability. However, the relationship between age and plaque inflammation has not yet been fully clarified. The aim of our study was to determine if age-dependent plaque vulnerability is associated with increased plaque inflammation.

• Author: Helena Grufman; Alexandru Schiopu; Andreas Edsfeldt; Harry Björkbacka; Mihaela Nitulescu; Marie MN Nilsson; Ana Persson; Jan Nilsson; Isabel Goncalves
• Department/s: EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies
• Publishing year: 2014
• Language: English
• Pages: 177-182
• Publication/Series: Atherosclerosis
• Volume: 237
• Issue: 1
• Full text: - 330 kB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25240113?dopt=Abstract; http://dx.doi.org/10.1016/j.atherosclerosis.2014.08.042
• Document type: Journal article
• Publisher: Elsevier
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Translational Studies
• ISBN/ISSN/Other: ISSN: 1879-1484