A solid target system with remote handling of irradiated targets for PET cyclotrons.

Summary, in English

A solid target system was developed for a PET cyclotron. The system is compatible with many different target materials in the form of foils and electroplated/sputtered targets which makes it useful for production of a wide variety of different PET radionuclides. The target material is manually loaded into the system. Remote handling of irradiated target material is managed with a pneumatic piston and a vacuum technique which allows the targets to be dropped into a shielded transport container. To test the target performance, proton irradiations (12.8MeV, 45μA) of monoisotopic yttrium foils (0.64mm, direct water cooling) were performed to produce (89)Zr. The yields were 2200±200MBq (1h, n=13) and 6300±65MBq (3h, n=3).

• Author: Jonathan Siikanen; Thuy Tran; T G Olsson; Sven-Erik Strand; Anders Sandell
• Department/s: Medical Radiation Physics, Lund; Lund University Bioimaging Center; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publishing year: 2014
• Language: English
• Pages: 294-301
• Publication/Series: Applied Radiation and Isotopes
• Volume: 94
• Links: http://www.ncbi.nlm.nih.gov/pubmed/25265518?dopt=Abstract; http://dx.doi.org/10.1016/j.apradiso.2014.09.001
• Document type: Journal article
• Publisher: Elsevier
• Topic: Radiology, Nuclear Medicine and Medical Imaging
• Status: Published
• ISBN/ISSN/Other: ISSN: 0969-8043