A correlation found between contact allergy to stent material and restenosis of the coronary arteries.
Author
Summary, in English
BACKGROUND: Metallic implants, stents, are increasingly being used especially in patients with stenosis of the cardiac vessels. Ten to thirty per cent of the patients suffer from restenosis regardless of aetiology. We have shown increased frequency of contact allergy to stent metals in stented patients. OBJECTIVES: To we evaluate whether contact allergy to stent material is a risk factor for restenosis. METHODS: Patients with stainless steel stents, with or without gold plating, were epicutaneously tested and answered a questionnaire. The restenosis rate was evaluated. RESULTS: We found a correlation between contact allergy to gold, gold stent, and restenosis (OR 2.3, CI 1.0-5.1, P = 0.04). The risk for restenosis was threefold increased when the patient was gold allergic and stented with a gold-plated stent. An increased degree of chest pain in gold-allergic patients stented with gold-plated stent was found. CONCLUSIONS: We found a correlation between contact allergy to gold, gold-stent, and restenosis. It may be of importance to consider contact allergy when developing new materials for stenting.
Department/s
Publishing year
2009
Language
English
Pages
158-164
Publication/Series
Contact Dermatitis
Volume
60
Issue
3
Links
Document type
Journal article
Publisher
Wiley-Blackwell
Topic
- Dermatology and Venereal Diseases
Status
Published
Research group
- Occupational and Environmental Dermatology
ISBN/ISSN/Other
- ISSN: 0105-1873