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Receptor binding mimetics: a novel molecularly imprinted polymer

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Author

Summary, in English

A novel molecularly imprinted polymer was prepared by copolymerization of trimethylolpropane trimethacrylate (1) and methacrylic acid (3) in the presence of a dipeptide acting as the template. The recognition capability of the synthetic receptor-like binding sites produced in the polymer network for the peptide was demonstrated by using the polymer as a chiral stationary phase in HPLC. The polymer was superior to previously reported molecularly imprinted polymers in that unusually high racemic resolution and load capacity were demonstrated.

Publishing year

1995

Language

English

Pages

3563-3566

Publication/Series

Tetrahedron Letters

Volume

36

Issue

20

Document type

Journal article

Publisher

Elsevier

Topic

  • Biochemistry and Molecular Biology

Status

Published

Research group

  • Nanomedicine and Biomaterials

ISBN/ISSN/Other

  • ISSN: 0040-4039