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Is craniofacial dysmorpholgy correlated with structural brain anomalies in schizophrenia?

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Author

  • BD Kelly
  • Thomas McNeil
  • A Lane
  • Karin Henriksson
  • A Kinsella
  • I Agartz

Summary, in English

This study aimed to examine the relationship between craniofacial dysmorphology and anomalies of brain morphology in schizophrenia. Assessments of craniofacial dysmorphology and magnetic resonance imaging of brain were performed independently of each other and blind to each other in 24 males with schizophrenia and 16 male controls. Ventricular cerebrospinal fluid volume was negatively correlated with total dysmorphology score in males with schizophrenia (i.e., the larger the ventricular cerebrospinal fluid volume, the lower the total dysmorphology score) but not in male controls. These findings suggest that craniofacial dysmorphology and anomalies of brain morphology may be associated with independent processes in the etiology of schizophrenia.

Publishing year

2005

Language

English

Pages

349-355

Publication/Series

Schizophrenia Research

Volume

80

Issue

2-3

Document type

Journal article

Publisher

Elsevier

Topic

  • Psychiatry

Keywords

  • human
  • anthropometry
  • schizophrenia
  • magnetic resonance imaging
  • development
  • causality

Status

Published

ISBN/ISSN/Other

  • ISSN: 0920-9964