A catalytic and mechanistic investigation of a PCP pincer palladium complex in the Stille reaction

Summary, in English

In an improved procedure, the complex {2,6-bis[(diphenylphosphino)methyl]benzene}chloropalladium(II) (1) was synthesised as its THF adduct and the structure was determined by X-ray crystallography. The catalytic properties of the derivative {2,6-bis[(diphenylphosphino)methyl]benzene} (trifluoroacetato)palladium(II) (2) was investigated in the Stille reaction. Complex 2 proves to be an excellent catalyst for the C-C cross-coupling between trimethyl phenyl stannane and aryl bromides using a very low catalyst loading (0.1-0.0001%), giving high turnover numbers (TONs) up to 6.9 x 10(5). A kinetic investigation of the catalytic reaction suggests a heterogeneous colloidal palladium catalyst formed from the PCP Pd(II) pre-catalyst.

• Author: Daniel Olsson; Patrik Nilsson; Mostafa El Masnaouy; Ola Wendt
• Department/s: Centre for Analysis and Synthesis; Department of Chemistry
• Publishing year: 2005
• Language: English
• Pages: 1924-1929
• Publication/Series: Dalton Transactions
• Volume: 2005
• Issue: 11
• Links: http://dx.doi.org/10.1039/b417908k
• Document type: Journal article
• Publisher: Royal Society of Chemistry
• Topic: Organic Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 1477-9234