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Prenylated isoflavanone from the roots of Erythrina sigmoidea

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Author

Summary, in English

A novel prenylated isoflavanone, sigmoidin I, has been isolated from the roots of Erythrina sigmoidea, in addition to the known isoflavones, corylin and neobavaisoflavone and the known pterocarpan, phaseollidin. Its structure was established as 7,4'-dihydroxy-3'-methoxy-5'-(3-methylbut-2-enyl) isoflavanone by means of spectroscopic analyses and chemical transformations. Neobavaisoflavone displayed antifungal potency in vitro with minimum inhibitory concentrations against Aspergillus fumigatus and Cryptococcus neoformans, of 50 mg ml-1.

Publishing year

1994

Language

English

Pages

1047-1051

Publication/Series

Phytochemistry

Volume

36

Issue

4

Document type

Journal article

Publisher

Elsevier

Topic

  • Dermatology and Venereal Diseases

Keywords

  • Erythrina sigmoidea
  • Leguminosae
  • roots
  • sigmoidin I
  • neobavaisoflavone
  • corylin
  • phaseollidin
  • antifungal activity

Status

Published

ISBN/ISSN/Other

  • ISSN: 0031-9422