Decreased levels of stem cell factor in subjects with incident coronary events.

Summary, in English

It has been proposed that vascular progenitor cells play an important role in vascular repair, but their possible clinical importance in cardiovascular disease has not been fully characterized. Vascular endothelial growth factor A, placental growth factor and stem cell factor (SCF) are three growth factors that are important in recruiting vascular progenitor cells. In this study, we investigated the association between the plasma levels of these growth factors and incident coronary events (CEs).

• Author: Maria Wigren; Sara Rattik; Karin Hultman; Harry Björkbacka; Gunilla Nordin Fredrikson; Eva Bengtsson; Bo Hedblad; A Siegbahn; Isabel Goncalves; Jan Nilsson
• Department/s: EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health; Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Epidemiology; Cardiovascular Research - Translational Studies
• Publishing year: 2016
• Language: English
• Pages: 180-191
• Publication/Series: Journal of Internal Medicine
• Volume: 279
• Issue: 2
• Full text: - 4 MB; Download statistics
• Links: http://www.ncbi.nlm.nih.gov/pubmed/26467529?dopt=Abstract; http://dx.doi.org/10.1111/joim.12443
• Document type: Journal article
• Publisher: Wiley-Blackwell
• Topic: Cardiac and Cardiovascular Systems
• Status: Published
• Research group: Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Epidemiology; Cardiovascular Research - Translational Studies
• ISBN/ISSN/Other: ISSN: 1365-2796