Motor and non-motor predictors of illness-related distress in Parkinson's disease.

Summary, in English

OBJECTIVE: To identify motor and non-motor symptoms independently associated with distress in Parkinson's disease (PD). METHOD: Clinical and patient-reported data from 118 people with PD (mean age and PD-duration, 64 and 8 years) were analyzed regarding associations with patient-reported distress using multiple regressions (controlling for age). RESULTS: Non-motor symptoms independently associated with distress were pain, fatigue, sleep, depression and anxiety (R(2), 0.81). The only significant motor aspect was mobility (R(2), 0.31). When considering both motor and non-motor symptoms, fatigue, pain, depression and sleep showed independent associations with distress (R(2), 0.76). CONCLUSION: Distress in PD is primarily associated with non-motor features.

• Author: Catharina Sjödahl Hammarlund; Peter Hagell; Maria H Nilsson
• Department/s: Human Movement: health and rehabilitation; Department of Health Sciences; Sustainable occupations and health in a life course perspective; MultiPark: Multidisciplinary research focused on Parkinson´s disease
• Publishing year: 2012
• Language: English
• Pages: 299-302
• Publication/Series: Parkinsonism & Related Disorders
• Volume: 18
• Issue: Nov 16
• Links: http://www.ncbi.nlm.nih.gov/pubmed/22100143?dopt=Abstract; http://dx.doi.org/10.1016/j.parkreldis.2011.10.015
• Document type: Journal article
• Publisher: Elsevier
• Topic: Neurology
• Status: Published
• Research group: Human Movement: health and rehabilitation; Sustainable occupations and health in a life course perspective
• ISBN/ISSN/Other: ISSN: 1873-5126